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China has emerged as a pivotal player in the global titanium dioxide industry, with its importers playing a crucial role in shaping the dynamics of this sector. Titanium dioxide, also known as TiO2, is a white pigment widely used in various applications such as paints, plastics, paper, and cosmetics. The country's growing demand for this versatile compound has led to an increase in import activities, making Chinese importers a vital link between domestic consumers and international producers.

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In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”

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